Objective To investigate the status of stigma and job withdrawal behavior in breast cancer survivors after return to work, to analyze the relationship between them and the related factors of job withdrawal behavior, so as to provide reference for targeted intervention. Methods A total of 314 breast cancer survivors who returned back to work after treatment were investigated using the Social Impact Scale and Job Withdrawal Behaviors Scale. Results The samples scored 43.14±10.26 on stigma and 3.86±0.67 on job withdrawal behavior. Stigma was significantly positively correlated with job withdrawal behavior (P＜0.01). Multiple linear regression analysis showed that stigma, age, treatment type, and length of time to return to work were factors associated with job withdrawal behavior (adjusted R2=0.342,P＜0.01 for all). Conclusion Breast cancer survivors who returned to work have mode-rate stigma and job withdrawal behavior, and their job withdrawal behavior is related to stigma. Medical staff need to strengthen transitional care, and pay more attention to those who report severe stigma, who are younger, who have received surgery and targeted therapy, and who return to work in a short amount of time, thus to improve their cognition and self-confidence and to adapt the society.