Objective To real time monitor nursing quality indicators through a real-time monitoring database of nursing quality indicators, and to provides data support for nursing quality management. Methods Based on the existing nursing quality indicators, we used computer language to develop a real-time nursing quality indicators monitoring database, which has been linked to various databases within the hospital, and automatically docks and acquires data from hospital units, and performs analysis and display for computing and comparison. Results Data acquisition, analysis and display of 402 nursing quality indicators were achieved.Fifthty nursing quality indicators in 2018 were significantly improved from 2017 readings. Conclusion The establishment of the real-time monitoring system for nursing quality indicators, helps build a dedicated database for nursing quality control to ensure timely and effective utilization of data, improve the quality of nursing care, and promote precision management.