Objective To describe job satisfaction of pediatric ICU nurses from 3A hospitals in China. Methods A total of 1 414 nurses working in pediatric ICUs from 25 hospitals of 16 provinces and cities nationwide were selected to fill out the Nurses Job Satisfaction Scale （NJSS）. Results The score of nurse job satisfaction was 124.92±18.61 （average item score 3.29±0.49）, with the dimension of relationship with colleagues scoring the highest, at （3.95±0.51）, and the dimension of salaries and welfares scoring the lowest, at （2.56±0.88）. Multivariate linear regression analysis showed that the regions where the hospital is located, the types of hospitals, nurses′ education levels, monthly income, length of service, whether being a certified ICU specialist could affect nurses job satisfaction. Conclusion Job satisfaction among pediatric ICU nurses was at medium level. To improve nurses′ job satisfaction, such measures as balancing the domestic resources, boosting effective cooperation among ICU staffers, enhancing nurses′ pay and welfares, building up a training system for nurses with advance degrees and longer service time, strengthening certification of pediatric ICU specialist nurses, are suggested.