Objective To analyze the correlation between perceived benefit and empirical avoidance among caregivers of senile dementia patients, and to provide reference for their mental health care. Methods A total of 142 caregivers of senile dementia patients were investigated using the Benefit Finding Scales （BFS） and the Acceptance and Action Questionnaire-2nd Edition（AAQ-Ⅱ）. Results The total average score of BFS among the caregivers was （2.03±0.31）, and the total mean score of AAQ-Ⅱ was （4.98±0.57）, and the BFS score negatively correlated with the score of AAQ-Ⅱ （r=-0.702，P＜0.01）. Conclusion The perceived benefit among caregivers of senile dementia patients is at a low level, and empirical avoidance was at a moderate level, and taking measures to enhance their perceived benefit is conducive to improving their empirical avoidance, then improving their mental health.