Objective To summarize the available best evidences on management of post-stroke dysphagia among adult patients, and to help improve effect of management. Methods We searched the such databases as BMJ best practice, up to date, Cochrane Libra-ry, National Guideline Clearing house, Joanna Briggs Institute Library, RANO, CINAHL, PubMed, GIN, CGN, CNKI and CBM, to collect all the evidence regarding management of post-stroke dysphagia among adult patients. Appraisal of Guidelines for Research & Evaluation Ⅱ (AGREE Ⅱ) was used to appraised the evidence, and the Joanna Briggs Institute Levels of Evidence and Grades of Recommendation (2014) were used to rate the evidence. Results A total of 15 pieces of evidence feasible and applicable in clinical context were summarized from 21 publications, covering such aspects as swallowing identification, screening, treatment, drug delivery principles, nutritional support and oral care. Conclusion The best evidence selected in this study can be applied in the management of dysphagia in adult stroke patients. Before application of the evidence in clinical context, it is necessary to consider the facilitators and barriers, and patients′ willingness and preferences, and select individual specific evidence.