Objective To explore the effect of targeted temperature management in patients with severe abdominal trauma. Methods A total of 50 patients with abdominal trauma hospitalized in 2016 were selected as the control group, whose body temperature was kept by using routine warming methods. Another 47 patients with abdominal trauma hospitalized in 2015 were assigned into the intervention group, who received target temperature management. The length of time from hospital admission to damage-control-surgery (DCS), the temperatures at the two time points, serum pH values, blood coagulation indexes between the 2 groups were compared. Record and compare the two groups of patients in ICU after 0 h, the Traumatic resuscitation time, pH, lactic acid, blood coagulation reaction time （R）, clotting time （K）, Angle of solidification （alpha Angle）, maximum amplitude （MA）, fibrinolysis rate （LY30） and the percentage of fibrinolysis （EPL）. Results The time to DCS, the above mentioned temperatures, serum pH values, lactic acid, blood coagulation reaction time (R values) and clotting time (R values) between the 2 groups had significant differences, all favoring the intervention group （P＜0.05,P＜0.01）. The results of angle of solidification （alpha Angle）, maximum amplitude （MA）, fibrinolysis rate （LY30） and the percentage of fibrinolysis （EPL） had no significant differences between the 2 groups (P＞0.05 for all）. Conclusion Targeted temperature management strategy can significantly lower the occurrence rate of hypothermia in trauma patients, prevent the development of acidosis and coagulation dysfunction, and save time for patients awaiting the deterministic operation.