Objective To evaluate the effect of finger exercise on relief of swelling and pain at the affected limb of patients undergoing transradial percutaneous coronary intervention (PCI). Methods A total of 196 patients receiving elective transradial PCI were assigned to a control group of 99 and an intervention group of 97. The control group was given conventional care, while the intervention group was subjected to finger exercise. The circumference of the palm, pain intensity and bleeding of the two groups were observed. Results The intervention group had a smaller circumference of the palm at postoperative 4 and 12 h and milder pain intensity compared with the control group （P<0.05,P<0.01）. There was no significant difference in bleeding between the two groups (P>0.05). Conclusion Finger exercise could alleviate swelling and pain intensity of the surgical limb without increasing bleeding at radial assess site in patients undergoing percutaneous coronary.