Objective To describe the status and influencing factors of physical activity in patients with chronic kidney disease （CKD）, and to provide basis for intervention and guidance regarding physical activity for CKD patients. Methods A total of 272 patients with stage 1 to 4 CKD were invited to complete a self-designed demographic questionnaire and International Physical Activity Questionnaire (long version). Results There were 68 （25.0%）,152 （55.9%） and 52 patients （19.1%） at the level of high, moderate and low level of physical activity respectively; the median weekly metabolic equivalent of task (MET) of work, transportation, housework and leisure exercise were 0,0,585 and 495 （MET-min/week）, respectively; the main type of physical activity was housework （41.4%）.Only 146 （53.7%） patients reached an activity level recommended by guidelines.Logistic multivariate regression analysis showed that men （OR=2.003,P=0.014）, young and middle ages （youth:OR=2.545,P=0.019, middle age:OR=2.088,P=0.042） and those with at least an associate′s degree （OR=2.349,P=0.012） were risk factors for being unable to reach a physical activity level recommended by guidelines. Conclusion Patients with stage 1 to 4 CKD have insufficient physical activity, which is significantly lower than the normal population. Individualized physical activity guidance and nursing intervention should be given to male, young and middle-aged and highly educated patients to improve their physical activity, disease outcomes and quality of life.