Objective To explore the effect of self-management intervention in patients in the convalescent stage of stroke. Methods A total of 160 patients in the convalescent stage of stroke from 6 3A hospitals in east, south, west, north, and central Fujian province were randomized into a control group, who were subjected to routine TCM convalescent stroke care plan, and an observation group, who were additionally assigned to receive self-management intervention.The Self-management Behavior Assessment Scale, the Chronic Disease Management Self-efficacy Scale and the Stroke Patient′s Quality of Life Scale were used to evaluate self-management behaviors and quality of life of the two groups before, 3 months after, and 6 months after intervention. Results After intervention, self-management level, self-efficacy and quality of life of the observation group were significantly better than those of the control group （P＜0.01 for all）. Conclusion Self-management intervention can significantly improve self-efficacy and quality of life of patients in the convalescent stage of stroke.