Objective To investigate the optimal feeding time and safety in patients with mild acute pancreatitis, and to promote patients′ recovery. Methods A total of 195 patients with mild acute pancreatitis were categorized into two groups according to their feeding time: 77 patients were fed within 24 hours of admission, and the rest 118 patients were fed at 24-72 h after admission. Factors influencing early oral feeding were analyzed and the impact of feeding within 24 h of admission on patients′ condition was evaluated. Results Significant differences were found in body mass index, the National Early Warning score at admission and 24 h after admission, the total Gastroparesis Cardinal Symptom Index (GCSIR) score and dimension scores of bloating and satiety at admission and 24 h after admission, and 24 h fluid intake volume after admission in patients fed within 24 h of admission compared with those fed 24-72 h after admission (P＜0.05, P＜0.01). The NEWS score and dimension score of satiety of the GCSIR at admission as well as bloating score at 24 h after admission were risk factors of early feeding within 24 h of admission (OR=1.230-1.490). The severity of disease condition change and length of hospital stay was significantly milder/shorter in patients fed within 24 h of admission compared to those fed 24-72 h after admission (P＜0.05, P<0.01), but there was no significant difference in feeding intolerance rate between patients fed within 24 h and those fed 24-72 h after admission (P＞0.05). Conclusion Patients with higher NEWS score and GCSIR score have a higher risk of delayed feeding. Feeding performed within 24 h of admission does not lead to feeding intolerance, which can accelerate the recovery of patients.