Objective To explore the effect of modularized dietary intervention on constipation and lipid level in patients undergoing primary PCI. Methods A total of 166 patients with acute myocardial infarction undergoing primary PCI were divided into a control group and an observation group chronologically, with 83 in each. The control group was given conventional education about lowsalt and lowfat diet, while the observation group received modularized dietary instruction list to manage patients′daily intake. Results The daily energy intake and incidence of constipation was significantly less/lower in the observation group than that in the control group during hospital stay (P<0.01 for both). The levels of triglyceride and lowdensity lipoprotein cholesterol were significantly lower, whereas the highdensity lipoprotein cholesterol level was significantly higher in the observation group compared with the control group at postoperative 7th day and at 1 month after discharge (P<0.05, P<0.01). 〖WTHZ〗Conclusion〖WTBZ〗 Modularized dietary intervention can ameliorate lipid level and reduce constipation in AMI patients undergoing primary PCI.