Abstract:Objective To summarize the best evidence of functional exercise for patients with venous leg ulcer, and to provide reference for clinical practice. Methods We searched databases and resources of evidencebased medicine, e.g. BMJ best practice, Registered Nurses′ Association of Ontario(RNAO), National Guideline Clearinghouse(NGC), Scottish Intercollegiate Guideline(SIGN), JBI Evidence Summary, Cochrane Library, PubMed, SinoMed and Wound, Ostomy and Continence Nurses Society (WOCN) to collect guidelines, summaries and systematic reviews concerning functional exercise for venous leg ulcers. Results Four guidelines and one systematic review were included. Then we extracted 13 best evidence and categorized into 5 dimensions of recommendations, including functional exercise, gait assessment, affected limb elevation, health education, and multidisciplinary collaboration. Conclusion Healthcare workers should consider patient preference and clinical situation to select reasonable evidence, thus to standardize functional exercise for patients with venous leg ulcers and enhance therapeutic effect.