Objective To understand the levels of nurses′ reflective practice and innovative behavior, to explore the impact of nurses′ reflective practice on their innovative behavior, and to provide reference for promoting nurses′ innovative behavior.Methods From April to June 2024, a questionnaire survey was conducted among 1,030 clinical nurses from four tertiary hospitals in Chengdu using the General Information Questionnaire, the Reflective Practice Questionnaire for Nurses, and the Innovative Behavior Scale for Nurses.Results The score of nurses′ reflective practice was (146.72±12.63) points; the score of nurses′ innovative behavior was (33.43±4.36) points.Nurse′ reflective practice was positively correlated with the innovative behavior (r=0.552,P＜0.05).Nurses′ reflective practice, education level, and whether they have participated in innovation-related activities or projects before were the main influencing factors of nurses′ innovative behavior (all P＜0.05), and nurses′ reflective practice could explain 42.0% of the total variance.Conclusion Both reflective practice and innovative behavior among nurses are at moderate levels.Nursing ma-nagers should encourage and guide nurses to engage in more open reflective practice during the nursing process, develop new knowledge and insights through reflection, and focus on nurses with lower education levels and those who have not participated in innovation-related activities or projects before, thereby further promoting the emergence of nurses′ innovative behavior.