Objective To evaluate the application effects of a full process intrathecal analgesia management program for cancer pain patients based on Timing It Right Theory.Methods Patients undergoing intrathecal analgesia for cancer pain were divided into a control group and an observation group of 49 cases each according to the admission order.The control group received routine nur-sing care, while the observation group was subjected to a full process intrathecal analgesia management program based on Timing It Right Theory.This program was developed through literature research, needs assessment, and expert consultation, including targeted nursing management measures for five stages:pre-intrathecal analgesia, clinical treatment, discharge preparation, discharge adjustment, and post-discharge adaptation.Pain intensity, adverse reaction incidence, and quality of life were evaluated before and three months after the intervention.Results Three months after intervention, the pain score of the observation group was significantly lower than that of the control group, and the quality of life score was significantly higher (both P＜0.05); there was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05).Conclusion The implementation of a full process intrathecal analgesia management program based on Timing It Right Theory can effectively improve pain relief, reduce the incidence of treatment-related adverse reactions, and enhance the quality of life of patients.