Accurate positioning of the tip of a central venous catheter (CVC) inserted via the peripheral vein is a commonly used technique in the field of peripherally inserted central catheters (PICC).This practice is crucial for optimizing drug delivery and reducing complications.This article provides a review of the applications, advantages, limitations, and appropriate conditions of PICC tip positioning techniques in fields such as imaging, ultrasound guidance, intracavitary electrocardiography, electromagnetic navigation, and deep learning models, aiming to offer insights for clinical practice.