Objective To clarify the definition and defining characteristics of mobolity limitation in patients.Methods A systematic search of Chinese and English language databases was conducted to review relevant literature on mobolity limitation. Concept analysis was conducted to define, describe, and delimit the concept of mobolity limitation. Results The defining attributes of mobolity limitation were categorized into three aspects: physical function decline, impaired performance of activities of daily living (ADL), and social participation restriction. The antecedents were pathological damage, perceived motor impairment, and environmental constraints. The consequences included increased health risks, heightened negative emotions, and social function impairment. Evaluation indicators included the Global Activity Limitation Indicator (GALI) and ability to perform ADL. Conclusion Clarifying the concept of mobolity limitation is beneficial for a comprehensive assessment of patients′ mobolity limitation, the formulation of tailored rehabilitation plans, the understanding of the causes of mobolity limitation, and the scientific implementation of intervention strategies.