Objective To analyze and clarify the concept of interoception among patients with chronic diseases, in order to provide reference for nursing practice.Methods Literature related to interoception in patients with chronic diseases in PubMed, Cochrane Library, CINAHL, Web of Science, Embase, CNKI, Wanfang Data, VIP.com, and SinoMed were systematically searched, and the included literature was analyzed by using Rodgers′ evolutionary concept analysis method.Results A total of 37 literature were included, containing 6 Chinese literature and 31 English literature.The conceptual attributes of interoception among patients with chronic diseases encompass three aspects:accurate interpretation of physiological signals in the body, acute perception of fluctuations in physiological states and context-based dynamic changes in perception.Antecedent variables comprise demographic factors, disease related characteristics, psychological factors, and social support. Consequences involve optimizing emotional states, enhancing self-care abilities, and improving clinical outcomes.Conclusion Clarifying the concept of interoception in patients with chronic diseases may provide ideas for the future development of specific assessment tools for interoception in patients with different chro-nic diseases and the construction of localized intervention strategies in China.