Objective To analyze the status quo and influencing factors of learned helplessness in postoperative patients with oral cancer, so as to provide reference for the clinical development of targeted intervention measures.Methods A total of 205 patients with oral cancer were investigated by the general information questionnaire, the Learned Helplessness Scale (LHS), Distress Disclosure Index (DDI) and Brief 2-Way Social Support Scale, and the influencing factors were analyzed.Results The score of LHS was （43.54±8.66）, the total score of DDI was （27.00±7.10） and the Brief 2-Way Social Support Scale score was （36.27±7.15）.The results of regression analysis showed that per capita monthly family income, clinical stage, self-disclosure and bidirectional social support were the main influencing factors of learned helplessness in patients with oral cancer after surgery （all P＜0.05）, with self-expression and bidirectional social support explaining 14.6% of the total variance.Conclusion The level of learned helplessness is high in postoperative oral cancer patients, and healthcare professionals should focus on patients with low per capita monthly fa-mily income, severe clinical stage, low self-disclosure, and poor social support, and the learned helplessness can be reduced by improving patients′ self-disclosure ability as well as the level of bidirectional social support.