Objective To evaluate and integrate the best evidence on chronic wound pain management，providing reference for clinical practice. Methods Domestic and international specialized websites and databases were searched for evidence on chronic wound pain assessment and management in accordance with the "6S" evidence pyramid model. The time frame of the search was from the establishment of the database to April 2024. Results A total of 12 papers were included, including 1 guideline, 4 evidence summaries, 3 best clinical practices, 2 systematic evaluations, 1 expert consensus, and 1 pilot study. Chronic wound pain management strategies were summarized in 32 entries in 5 dimensions: general principles of pain management, content of pain assessment, timing and tools for pain assessment, nonpharmacological interventions, and pharmacological interventions. Conclusion This study summarizes the current best evidence on chronic wound pain management, which can provide an evidence-based basis for clinical healthcare professionals to scientifically manage chronic wound pain, reduce patients′ pain and disease burden, and improve patients′ quality of life.