Objective To summarize the best evidence on perineal pain management in women after normal vaginal delivery, and to provide evidences for effective perineal pain management in clinic.Methods Systematic retrieval of clinical support decision-making system, domestic and international guide websites, websites of professional societies or associations and related databases was conducted to obtain literature on postpartum perineal pain management in normal vaginal delivery women, including clinical decision-making, evidence summary, best practices, guidelines, expert consensus, systematic reviews.The retrieval time limit was from the establishment of the databases or websites to November, 2023.Two researchers independently evaluated the quality of the lite-rature, and four researchers extracted and integrated the evidence according to the standardized extraction table, and determined the final best evidence through group discussion.Results Twenty articles were included, consisting of 3 clinical decisions, 4 evidence summaries, 4 guidelines, 4 pieces of expert consensus and 5 systematic reviews.Finally, 26 pieces of evidence were summarized and categorized into seven aspects:prevention of perineal trauma, suture of perineal wound, pain assessment, non-drug intervention, drug intervention, postpartum education and personnel training.Conclusion The summarized evidence on postpartum perineal pain management in women after normal vaginal delivery is scientific and comprehensive.Clinical medical staff can choose the evidence according to actual clinical situation and patients′ needs, and formulate relevant pain management measures to reduce the degree of perineal pain.