Objective To explore the impact of intelligent excretion care systems on nursing practices for critically ill patients and provide insights for the advancement of intelligent rehabilitation nursing. Methods A descriptive qualitative study was conducted from March to May 2024, involving semi-structured interviews with 12 nurses who had experience with intelligent excretion care systems. Data were analyzed using content analysis method. Results Three main themes emerged: (1) reduction in nursing workload (including decreased work stress and alleviation of physical and mental strain on nurses); (2) risks associated with the system′s use (including systemic risks and challenges to traditional care models); (3) nurses′ needs for system enhancement (such as a clear and intuitive interface, continuous comfort optimization, and the integration of convenience with precision). Conclusion The intelligent excretion care system positively reduces the physical burden on nurses. During its use, patient-centered adjustments are needed to achieve such aims as enhancing safety and reliability, precisionly quantifing clinical monitoring metrics, and further optimizing the system to meet patient needs.