Objective To develop a follow-up checklist for patients after liver transplantation, and to provide effective support for healthcare professionals in improving follow-up practices. Methods A draft of the follow-up checklist was constructed through literature review, semi- structured interviews, and expert panel discussions. The Delphi method was employed for two rounds of expert consultation, leading to revisions and the finalization of the checklist. Six liver transplant nurses were selected for face-to-face interviews and ten patients post-liver transplantation were selected for face-to-face follow-ups, during which the contents of the checklist were evaluated and refined. Results The follow-up checklist for patients post-liver transplantation included 4 primary indicators:physiological status and daily living guidance, psychological status and informational support, medical services, and social support, along with 15 secondary indicators and 51 tertiary indicators. The response rates from the two rounds of expert consultation were 93.75% and 100%, with expert authority coefficients of 0.93 and 0.94. The Kendall concordance coefficients for the first and second round for the primary, secondary, and tertiary indicators were 0.317, 0.146, 0.209, and 0.265, 0.248, 0.217, respectively (all P<0.05). Both nurses and patients expressed that the checklist contents were reasonable and comprehensive, de-monstrating strong professionalism and clinical practicality. Conclusion The developed follow-up checklist for patients after liver transplantation is structurally sound and content-rich, providing a reference for formulating and implementing follow-up plans for patients post-discharge.