Objective To construct an interprofessional collaborative sports rehabilitation scheme for patients after lumbar interbody fusion, and to evaluate its application effect. Methods One hundred and twenty patients undergoing lumbar interbody fusion were divided into a control group and an intervention group according to wards, with 60 cases in each group.The control group received routine rehabilitation nursing, while the intervention group received a sports rehabilitation scheme based on interprofessional collaboration model. Results Totally 59 cases in the control group and 58 cases in the intervention group completed the study. At different time points after the surgery, the lumbar spine function, pain, and fatigue scores of the intervention group were significantly lower than those of the control group (all P<0.05). Conclusion Implementation of the sports rehabilitation scheme based on interprofessional collaboration model for patients after lumbar interbody fusion, is beneficial for improving lumbar function, reducing pain, alleviating perioperative fatigue, and promoting patient rehabilitation.