Objective To understand the current status of parenting concerns in cancer patients with minor and young-adult children and to analyze its influencing factors, so as to provide a reference for improving their parenting concerns.Methods A total of 372 cancer patients were selected by convenience sampling method, then they were investigated by utilizing a general information questionnaire, the Parenting Concerns Questionnaire (PCQ), the Distress Disclosure Index (DDI), the Perceived Partner Responsiveness Scale (PPRS), and the Parenting Sense of Competence Scale (PSOC).Results Cancer patients scored 32.00(24.00, 41.00) points in PCQ.Generalized linear regression analysis showed that, educational background, age of the youngest minor child, health status of the child, whether the patient suffered from metastasis or recurrence, the score of the DDI, the PPRS, and the PSOC were the influencing factors of parenting concerns in cancer patients with minor and young-adult children ( all P＜0.05).Conclusion Parenting concerns in cancer patients with minor and young-adult children is at a low to moderate level, so medical staff should develop targeted interventions according to the influencing factors, in order to alleviate the parenting concerns in cancer patients.