Objective To observe the effects of Qianci acupuncture combined with Huolong cupping therapy on neck pain, cervical soft tissue tension, and quality of life in cervical spondylosis patients with neck pain.Methods A total of 105 cervical spondylosis patients with neck pain were randomized into a Qianci acupuncture group, a Huolong cupping group and a combined group, with 35 cases in each group.The Qianci acupuncture was given 5 times per week while the Huolong cupping was given twice per week for the corresponding group, and the intervention lasted for 2 weeks.The combined group was given Qianci acupuncture combined with Huolong cupping therapy with the same intervention frequency and course as the previous two groups.The three groups were followed-up 1 month after the intervention.Results Thirty-three cases in the Qianci acupuncture group, 34 cases in the Huolong cupping group and the combined group completed the study and follow-up.The time effect, group effect and group by time effect among the three groups in the pain score of Visual Analogue Scale (VAS) were statistically significant, and two weeks after the intervention, the VAS score of the combined group was significantly lower than those of the other two groups (all P＜0.05).Two weeks after the intervention, the work and displacement of cervical soft tissue of the combined group were significantly higher than those of the other two groups ( all P＜0.05).The time effect and group effect among the three groups in the score of Northwick-Park Neck Pain Questionnaire (NPQ) were statistically significant, and the score of the combined group were significantly lower than those of the other two groups at 2 weeks after the intervention and 1 month follow-up after the intervention (all P＜0.05).Conclusion Qianci acupuncture combined with Huolong cupping therapy can quickly relieve neck pain in patients with cervical spondylosis, improve the elasticity of neck muscle tissue, and alleviate the impact of neck pain on quality of life.