Objective To develop a Caregiver Preparedness Scale for PICU Transfer Children, and to test its reliability and validity.Methods Based on Meleis Transition Theory and Roy Adaptation Model, an initial scale was developed through literature review, expert consultation and pilot survey.Then it was used to investigate 397 conveniently selected caregivers of PICU transfer children to conduct item analysis and reliability and validity testing.Results The Caregiver Preparedness Scale for PICU Transfer Children consisted of 5 dimensions and 23 items.Five common factors were extracted by exploratory factor analysis, and the cumulative variance contribution rate was 69.294%; confirmatory factor analysis results showed, χ2/df=1.998,GFI=0.891,CFI=0.964,IFI=0.916,TLI=0.901,RMSEA=0.060.The Cronbach′s α coefficient of the scale was 0.906, which ranged from 0.835 to 0.963 for the 5 dimensions, and its split half reliability was 0.904.Conclusion The Caregiver Preparedness Scale for PICU Transfer Children has good reliability and validity, it can be used to assess the appropriate transfer time and caregiver preparedness for children transfer.