Objective To explore the application effectiveness of early warning score combined with a rapid response team for patients with severe preeclampsia. Methods Patients with severe preeclampsia who visited the emergency department from January to December 2020 were selected as the control group, and routine nursing methods were implemented.Patients with severe preeclampsia who visited the emergency department from July 2021 to June 2022 were included in the intervention group. The early warning rating scale was used to objectively evaluate pregnant women. If the early warning score triggered the rapid response system, the rapid response team was immediately activated to provide emergency rescue for patients. The maternal and infant outcomes of the two groups were compared. Results The control of systolic and diastolic blood pressure in the intervention group were better than that in the control group and the length of stay in the emergency observation unit for the intervention group was significantly reduced (both P <0.05). The incidence of HELLP syndrome, placental abruption, premature rupture of membranes, uterine atony, and postpartum hemorrhage in the intervention group was significantly lower than that in the control group (all P<0.05). The rates of premature birth, fetal distress, and neonatal ICU transfer were significantly lower in the intervention group than those in the control group (all P<0.05). Conclusion Early warning score combined with the rapid response team can effectively reduce adverse maternal and neonatal outcomes in patients with severe preeclampsia, contributing to the safety of both mother and baby.