This article describes the risk factors and preventive management measures for incontinence-associated dermatitis in severe patients.In addition to general risk factors, critical illness itself is a risk factor for the development of incontinence-associated dermatitis.This article mainly includes three aspects of the prevention and management of incontinence-associated dermatitis in severe patients:the construction of an incontinence-associated dermatitis prevention management system based on an information platform, the formulation of evidence-based prevention and management interventions, and the realization of diversified skin interventions with the help of new dressings and drugs.It is proposed that the prevention and management of incontinence-associated dermatitis in severe patients is complex and requires continuous and in-depth exploration by clinical nurses.