Objective To improve the effect of pre-post operation training for newly recruited nurses. Methods A total of 32 newly recruited nurses enrolled in 2019 were assigned into a control group, and another 30 newly recruited nurses enrolled in 2020 were regarded as an experimental group. The control group was trained pre-post operation using the traditional method, while the experimental group was trained utilizing the modified Peyton′s four-step approach. Results The operation skill score of the control group and the experimental group was (90.63±1.27) and （96.03±1.35） respectively, there was significant difference between the two groups (P＜0.01)，and the clinical practice ability score and the training satisfaction of the experimental group were significantly higher than those of the control group (P＜0.05, P＜0.01). Conclusion Application of modified Peyton′s four-step approach in pre-post operation training for newly recruited nurses, is conducive to encouraging newly recruited nurses′ learning activity and initiative, improving nursing skill training effect, and enhancing newly recruited nurses′ training experience and satisfaction.