Objective To construct an information technology platform for nursing management and to improve the management effect. Methods Based on the internal control theory and patient safety goal, an information technology platform was created, including four modules of quality control goal, quality inspection, training and rectification, and information communication. Two wards were selected for pilot study and then applied in the whole hospital. The effect was evaluated after one year of application. Results The incidence rates of falls, unplanned extubation and pressure ulcer were significantly decreased, whereas the reporting rate of potential nursing safety defects and nursing quality were significantly increased after application of the platform(P<0.01 for all). The overall satisfaction rate of 422 nurses using the platform was 93.84%. Conclusion The information technology platform for nursing management has good applicability, which can effectively reduce nursing risk and improve nursing quality.