Objective To explore the effect of manual lymph drainage in combination with Kegel exercise on patients developing stage Ⅰ lymphedema at the vulva after cervical cancer surgery. Methods Ten patients developing stageⅠlymphedema at the vulva after cervical cancer surgery were recruited to receive an intervention combining manual lymph drainage and Kegel exercise. The intervention stretched 28 days, with 20 sessions forming a treatment course. Results StageⅠlymphedema at the vulva gradually resolved upon completion of 0, 5, 10, 15 and 20 sessions. Lymphedema in 9 patients completely vanished at the completion of the 1st course, while partially resolved in 1 case. Conclusion It is important to pay attention to early identification and treatment of stageⅠlymphedema at the vulva. Manual lymph drainage in combination with Kegel exercise plays a positive role in rehabilitation of patients who suffer from stage Ⅰ lymphedema at the vulva after cervical cancer surgery, and improves the quality of life of the patients.