Objective To meet the needs of home care services among discharged patients by extending hospital care service. Methods The leadership group and working group of "Internet plus nursing service" were built to formulate three nursing service modes of hospital-family, hospital-community and hospital-community-family, then develop targeted information technology-assisted platforms and establish operating mechanism. Results After 4 months of implementation, 83 patients received 124 counts of nursing service, and no adverse event occurred. Patients scored 4.41±0.69 on satisfaction. Among 31 nurses who provided nursingservice, 64.5%-100% of them gave positive feedbacks on 10 evaluation items. Conclusion Implementation of hospital-driven "Internet plus nursing service" meets the needs of patients, which is conducive to promoting the development of nurses′ multi-site practice.