Objective To explore the effect of family centered empowering discharge planning for patients receiving preventive ente-rostomy.Methods A total of 65 hospitalized patients receiving preventive colostomy were randomly divided into a control group (n=32),who received routine nursing care and an intervention group (n=33), who additionally received family centered empowering discharge planning service. The 2 groups were measured with Chinese version of Colostomy Patients Quality of Life Scale and Discharge Readiness Scale. Results After the intervention, discharge readiness scores had significant differences between the 2 groups （P＜0.01）, likewise the quality of life scores （P＜0.05，P＜0.01）. Conclusion Family centered empowering discharge planning can improve discharge readiness and quality of life of patients receiving preventive enterostomy.