Objective To develop an empowerment scale for hypertensive patients and test the reliability and validity of the scale, and to provide a reference for measurement of empowerment in hypertensive patients. Methods The literature review method and Delphi technique based expert consultation method were used to construct the initial version of the Hypertensive Patients Empowerment Scale. Then 163 hypertensive patients from 2 3A hospitals in Fujian Province were selected for pre-survey using target sampling method. At last, 472 hypertensive patients from 6 3A hospitals and 2 community health service centers in Fujian Province were selected by target sampling method for formal investigation, and for further item screening and reliability and validity analysis. Results The final version of the scale included 4 first-level indicators, 9 second-level indicators, and 31 items. The content validityof the scale was 0.922. Exploratory factor analysis extracted 9 factors, and the cumulative variance contribution rate was 73.806%. Confirmatory factor analysis indicated that, RMSEA=0.049, IFI=0.946, CFI=0.945, PGFI=0.689, χ2/df=1.565, suggesting excellent model fit and good structural validity. The convergence validity of the first and second-level indicators ranged from 0.578 to 0.648, and from 0.439 to 0.857 respectively. The Cronbach′s α coefficient of the total scale was 0.885, the split-half reliability of total scale was 0.805. Conclusion The hypertensive patients empowerment scale has a good reliability and validity, and can be used for the assessment of the empowerment of patients with hypertension.