Objective To explore the application effect of mind mapping combining with scenario simulation in the standardized trai-ning of trauma first aid for emergency nurses. Methods A total of 62 standardized training nurses were divided into 2 groups chronologically, the 30 nurses enrolling from Jan to Dec 2017 were regarded as a control group, who were trained trauma first aid using traditional method; another 32 nurses enrolling from Jan to Dec 2018 were taken as an experimental group, who were trained utilizing mind mapping combining with scenario simulation. Results After the standardized training, the score of theoretical and skill examination in the experimental group were significantly higher than those of the control group, and the total score as well as the 7 dimension scores of Critical Thinking Disposition Inventory were significantly higher than those of the control group （P＜0.05,P＜0.01）. Conclusion The training using mind mapping and scenario simulation is conducive to improving critical thinking ability of standardized training nurses in emergency department and enhancing training effect, therefore the nurses could cooperate well in trauma first aid, and it is benefit to improve the nursing quality of trauma first aid.