Objective To describe the status of readiness for hospital discharge and its associated factors in patients with cervical cancer undergoing radical hysterectomy and requiring clean intermittent self-catheterization, and to provide references for targeted intervention. Methods A total of 132 patients with cervical cancer undergoing radical hysterectomy and requiring clean intermittent self-catheterization were investigated using the general information questionnaire, the Readiness for Hospital Discharge Scale and the Quality of Discharge Teaching Scale. Results They scored 92.45±12.34 on readiness for hospital discharge. Multiple linear regression analysis showed that place of residence, main caregivers and quality of discharge teaching were influencing factors of readiness for hospital discharge (P<0.05, P<0.01). Conclusion The readiness for hospital discharge was at a medium level in cervical cancer patients undergoing radical hysterectomy and requiring clean intermittent selfcatheterization. Medical personnel should strengthen discharge teaching and provide targeted interventions according to patients′ conditions, thus to ensure patient safety after hospital discharge.