Objective To explore the effects of implementing management by objective (MBO) approach on enhanced recovery after surgery (ERAS) program for children with Hirschsprung′s disease. Methods Seventysix children with Hirschsprung′s disease undergoing elective surgery were divided into two groups according to their parents′ willingness to accept or resist the ERAS program. The control group of 29 children were given routine treatment and nursing care, while the observation group of 47 children received MBO directed ERAS. Results Compared with the control group, the observation group had milder postoperative pain, earlier first passage of flatus and oral dietary intake, shorter hospital stay length, less hospital cost and higher patient satisfaction (P<0.01 for all). Conclusion Application of MBO approach in ERAS program for children with Hirschsprung′s disease can promote recovery of children, reduce hospital cost and enhance satisfaction of parents.